Directions from O'Hare International to Argonne National Laboratory
- Drive east (toward Chicago) on Interstate 90 to the exit for Interstate 294 south (toward Indiana).
- Go south on I-294 to the exit for Interstate 55 south (toward St. Louis).
294 is a toll road, so you will change for the automatic lanes. Alternatively, if you do not have exact change, you can use the manual lanes with a live toll taker.
- Take I-55 south to the South Cass Avenue exit (Exit No.273A).
- Turn left, after you exit I-55, to drive over the overpass. At this point you will see the sign for Argonne National Laboratory.
- Turn right onto Northgate Road, which is the Argonne entrance.
- Follow Northgate Road to the Argonne Visitor Center.
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